The evil mutants have returned and are seeking the location of the heroic X-men. Magneto kidnaps the Angel and plans to use him as bait to lure his teammates into a trap. The X-men will have to face this challenge on their own as their leader Professor X has lost his mutant powers!
The X-men have graduated from the academy. Professor Charles must leave them for a short time and his final gift to them is Cerebro! A machine to find other mutants. Meanwhile Magneto has a new plan to defeat the X-men by recruiting the Blob!
Professor X has left on a secret mission, leaving Cyclops as the leader of the X-Men. It doesn't take long for Cyclops to take his first test, when Hank McCoy, annoyed for being treated like a menace by the general public, decides to leave the X-Men, and start a career on wrestling. However, there's another mutant around, another wrestler called.....
The X-Men's mutant radar is detecting a super strong mutant in the area, so strong that the radar gets broken. Of course, Professor X is interested in contacting this powerful mutant before Magneto and his Brotherhood of Evil Mutants do
After believing he has killed Iron Man, the Beast turns to fellow outcast mutants in the New Brotherhood of Mutants. As the team's plans becomes clear, the Beast is not sure their goal aligns with his morals.
With Nighthawk, the newest Defender sworn in, Valkyrie makes a fateful announcement. However, before their discussion can run its course Dr. Strange receives a call for help from a most surprising source.
Alpha the Ultimate Mutant has been born and the Defenders can but quake in his presence. However, if Magneto and his Brotherhood of Mutants are to be stopped, Dr. Strange and his crew must find a way to overcome this awesome menace.