City officials begin missing and the Avengers decide to investigate. At a meeting, Scorpio blows up the room and captures the team. This leads to an unveiling of the group Scorpio has been a part of since he began his attacks on S.H.I.E.L.D.

The Avengers head west, back to the Red Wolf's homeland, when they are suddenly attacked. Upon crashing the Scarlet Witch and Vision are surrounded and surrender. Meanwhile, Goliath and Red Wolf return to the Native American village to rally warriors.

The Avengers are captured by the Zodiac as all of Manhattan is taken hostage by Aries. The only Avenger member left in the city un-captured is the Black Panther who seeks help from his former ally Daredevil.

The Zodiac shifts their focus from Stark Industries and Iron Man to Daredevil. When Zodiac casts a net upon the crime-fighter, they inadvertently capture Madam Masque as well.

Iron Man, Madam Masque, Nick Fury, and Daredevil wrap up their battle with the Zodiac and go their separate ways. When Tony gets fed up with being Iron Man he heads to Manhattan to live up his playboy lifestyle, that is, until an alien being invades the city.

The Avengers have their hands full when Gemini and the rest of the Zodiac bring a full frontal assault to Avenger's Mansion.

Taurus and the Zodiac have the Avenger's between a rock and a hard place with either their surrender or Mantis's death as their only options. But can such a choice truly be made?

Trapped by the mischievous Taurus, the Avenger's and the rebellious members of Zodiac find themselves trapped in an orbiting space prison. Meanwhile, Libra hatches a plan of his own.

With the sudden revelation of Libra's connection to Mantis neither she nor the rest of the Avengers know quite how to respond. The Swordsman on the other hand knows exactly what he must do and springs to action.

The Avengers have come to the Temple of Pama too late to save the priests but their trip has not been in vain as a far greater menace soon arises. All the while the mystery surrounding Mantis continues to unfurl.