The Angel is bombarded by radiation when an atomic bomb is tested at one of Tony Stark's installation. The radiation altered his personality and made him evil. Once Iron Man was trying to save him; now he is the one that needs saving from this young X-man.
When Calvin Zabo tries to get a job with Dr Blake, he is turned down by the knowing Doctor. Swearing revenge for his humiliation; Calvin Zabo recreates the infamous potion which changed Doctor Jekyll into Mister Hyde.
Odin agrees with Loki's suggestion of sending the Enchantress to steal Thor's affection away from Jane Foster. When things don't go her way, she decides to rule out the other woman from the equation altogether with the help of the Executioner!
Being too much of a threat to be left to his own devices, the Avengers start a search for the Hulk. He manages to evade them by escaping into the Atlantic Ocean. Where he finds a most unlikely ally, the Sub-mariner!
Max Dillon was an ordinary electric pole-man when a lightning bolt struck him, giving him the power to generate electricity from his own body! Now as Electro nothing can stop him from taking anything he wants except the amazing Spider-man!
The Wizard has escaped from prison with the help of his new invention, an anti-gravity machine. With it he plans to capture the Human Torch and steal his identity. He may find the means to perfect his diabolical machine!
The Rabble Rouser has convinced the city council to place an ordinance stopping the Human Torch from flaming on in public. Little do the people of New York know that the street corner soap box fanatic is a Red agent!
Professor Garrett was captured by Giant-man and imprisoned for trying to sell scientific secrets to the Chinese Reds. The Reds paid his bail but he has revenge in his heart against Giant-man. So Garrett genetically engineers a flying steed and with a mechanical lance he has become the Black Knight!
Umberto was a contortionist in a Broadway show when he realized that his powers can serve him better as a thief than a performer. With a disguise and trained crows at his call, he became the Scarecrow!
The inventive genius of Alex Gentry has returned as the Porcupine! After being thwarted by Ant-man in their last encounter by liquid cement, the Porcupine has a new plan to exact his revenge on our hero!
After serving his prison term Doctor Otto Octavius has been released! Meanwhile Peter Parker is dealing with his feelings over the disappearance of Betty Brant. Will this affect him as Spider-man when he may have to stop Doctor Octopus for the second time?!
By saving a blind man from a runaway truck carrying radioactive materials, Matthew Murdock's life was changed forever. The accident left him blind but the radiation boosted the sensitivity of his other senses, giving him the power to become the Daredevil!
Doctor Octopus escaped from Spider-man in Philadelphia and has been on a crime spree ever since. Finally returning to New York to confront his nemesis, he kidnaps Betty Brant and uses her as bait to get a confrontation with the amazing Spider-man!