Captain America and the Beast rally the Avengers to investigate an attack perpetrated by the Brand Corporation, and end up facing off against the Squadron Supreme. Meanwhile, Thor and Moondragon travel back through time in an attempt to rescue Hawkeye.
The Avengers, in company of Patsy Walker, press deeper into the Brand Corporation base in pursuit of answers. When they happen across the discarded costume of the Cat, Patsy seizes her chance to become a super-heroine in her own right.
The Avengers have been transported to another version of Earth, the home world of the Squadron Supreme. In addition to these super-powered foes, they face the united strength of this world's armies which have fallen under the influence of the Serpent Crown.
Having returned from other-Earth, the Avengers face the remnants of Roxxon Oil's army, as well as a souped up Orka. As Thor rushes to their aid, Moondragon forces him to view his role among the Avengers from a new perspective.